Lizzie Mann, PhD student in Susan Duty’s lab at King’s College London Jennifer Martin, graduate student at the State University of New York at Buffalo in the Department of Pharmacology and Toxicology “Being able to sequence the transcriptome of cells from different physiological conditions has opened the door for identifying critical molecular markers for such disease states and will greatly aid in the development and / or identification of therapeutics.” Rebecca San Gil, Postdoctoral Research Fellow at the Queensland Brain Institute, University of Queensland I am very excited to be starting a new project in the new year involving CRISPR and I can’t wait to see what we will learn using this technique”. “I think it is the versatility of CRISPR that makes it the greatest discovery of all time, CRISPR can be used to edit, knock-out, inhibit and activate genes. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) James Cleland, PhD Fellow at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)Ģ. Excitingly, some of these efforts are even in clinical trials and hopefully slowly working their way into the clinic.” This has been an absolute game-changer for understanding the mechanisms underlying how biological systems work, but also the diseases that disturb them. “It has given scientists the power to surgically remove - and just as excitingly, monitor the activity of - genes and the regulatory elements that control them. To give science some extra love (as if we could love it any more), we’ve looked back on our conversations and interviews with our life science community to see which scientific discoveries you think are the greatest.įrom penicillin to genome editing to CRISPR, here’s a roundup of the greatest scientific discoveries of all time (in no particular order) which have been highlighted on our blog over the past year. What Are The Greatest Scientific Discoveries Of All Time?Īll scientific discoveries are amazing, and some are truly life changing.
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